Safe OTC Medications for Pregnancy


Heartburn, gas and bloating, upset stomach

  • Antacids for heartburn (Maalox, Mylanta, Rolaids, Tums)
  • Simethicone for gas pains (Gas-X, Maalox Anti-Gas, Mylanta Gas, Mylicon)

Cough or cold

  • Guaifenesin, an expectorant (Hytuss, Mucinex, Naldecon Senior EX, Robitussin DM)
  • Dextromethorphan, a cough suppressant (Benylin Adult, Robitussin Maximum Strength Cough, Scot-Tussin DM, Vicks 44 Cough Relief)
  • Guaifenesin plus dextromethorphan (Benylin Expectorant, Robitussin DM, Vicks 44E);Cough drops Vicks VapoRub
  • Avoid cold remedies that contain alcohol. Also avoid the decongestants pseudoephedrine and phenylephrine, which can affect blood flow to the placenta.

Pain relief, headache, and fever

  • Acetaminophen (Anacin Aspirin-Free, Tylenol)

Allergy relief

  • Sudafed, Benadryl, Zyrtec, Claritin, Normal Saline Spray, Neti-pot with packaged saline.

Constipation, hemorrhoids, and diarrhea

  • Psyllium (Konsyl-D, Metamucil, Modane Bulk, Perdiem) Polycarbophil (Equalactin, Fiber-Lax, FiberNorm, Konsyl-Fiber, Mitrolan)
  • Methylcellulose (Citrucel, Unifiber)
  • Other laxatives and stool softeners (Colace, Dulcolax, Maltsupex, milk of magnesia, MIRALAX)
  • Hemorrhoid creams (Anusol, Preparation H, Tucks), Anti-diarrhea medication Loperamide (Imodium, Kaopectate II, Maalox Anti-Diarrheal, Pepto Diarrhea Control)

Yeast infections and other fungal infections such as athlete’s foot

  • Clotrimazole (Cruex, Gyne-Lotrimin 3, Lotrimin AF, Mycelex 7)
  • Miconazole (Desenex, Femizol-M, Micatin, Monistat 3)
  • Terbinafine (Lamisil AT)
  • Tioconazole (Monistat 1, Vagistat 1)
  • Butoconazole (Femstat 3, Mycelex 3)
  • Butenafine (Lotrimin Ultra)
  • Tolnaftate (Absorbine Athlete’s Foot Cream, Absorbine Footcare, Genaspor, Tinactin)
  • Undecylenic Acid and derivatives (Cruex, Desenex, Fungi Cure, Tinacide)
  • Certain Cruex, Desenex, and Fungi Cure products may contain other antifungal agents not listed here that should not be used during pregnancy. Check the labels carefully.


  • Diphenhydramine (Benadryl, Maximum Strength Unisom SleepGels, Nytol, Sominex)
  • Doxylamine succinate (Unisom Nighttime Sleep-Aid)

First-aid preparations

  • Cortaid, Lanacort, Polysporin

Gastroesophageal reflux disease (GERD)

  • Cimetidine (Tagamet®)
  • Prilosec OTC


  • Simethicone (Gas-X ®, Mylicon ®, Phazyme ®)
  •  Christopher G. Seeker, MD

    Michael F. Phillips, MD

    Robert K. Cowan, MD

    Marco A. Uribe, MD

    Mark D. Akin, MD

  • Dr. Christopher Seeker and Dr. Robert Cowan have been named Austin Fit Magazine's Best of 2016 OB/GYN Doctor award winners! Their compassion for their patients, and dedication to the practice, is unmatched.

Austin Area Obstetrics, Gynecology, and Fertility
12200 Renfert Way, Ste. 100
Austin, TX 78758
Phone: 512-652-7001
Fax: 512-450-1146
Office Hours

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